货品编号： Bioss.bsm-33176M 品 牌： Bioss 品 名：Anti-eNOS一氧化氮合成酶-3（内皮型）单克隆抗体 规 格： 100ul 研究领域 细胞生物神经生物学信号转导合成与降解内皮细胞 抗体来源 Mouse 克隆类型 Monoclonal 克隆号 8G1 交叉反应 Human,Mouse,Rat, 产品应用 WB=1:500-1000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 133kDa 细胞定位 细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 Recombinant human eNOS Protein: 亚型 IgG 纯化方法 affinity purified by Protein G 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed PubMed

产品介绍 Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline.

Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti

pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); inducible NOS (iNOS) or

macrophage NOS (mNOS); and endothelial NOS (eNOS).

eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with

myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the

diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate.

eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.