货品编号Bioss.bs-1696R

品牌Bioss

品名Anti-DR5肿瘤细胞调亡素/死亡受体5抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量48kDa

细胞定位细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from rat DR5:301-381/381 <Cytoplasmic>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain.

This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and

transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor

protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one

non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]