货品编号: bioss.bs-17523R-10ul 品 牌:bioss 品 名:Rabbit Anti-OSCAR antibody 试用装 规 格: 10ul 产品描述:
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an
osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays
critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in
oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants
encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Function: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
Subcellular Location: Secreted and Cell membrane.
Similarity: Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. Contains 2 Ig-like (immunoglobulin-like) domains.
SWISS: Q8IYS5
Gene ID: 126014
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