货品编号Bioss.bs-1531R

品牌Bioss

品名Anti-ATF4活化转录因子4抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg /test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量38kDa

细胞定位细胞核 细胞浆 细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ATF4:251-351/351

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding

protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated

and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene

belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response

element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that

is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA

binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are

located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]