货品编号： SignalChem.C14-10BG-10 品牌： SignalChem 品名： KINASES - CAMK2 gamma, Active 规格： 10 ug

产品描述：

Description: Full-length recombinant human CAMK2gamma was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. Species: Human Tag: GST tag Expression System: Sf9 insect cells using baculovirus Sequence: Full length Genbank Number: NM_172169 Specific Activity : Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity : Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation

and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Applications : Kinase Assay, Western Blot Molecular Weight : ~86 kDa Gene Aliases : CAMKG, CAMK, CAMK-II, MGC26678, CAMK2G Formulation : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. Scientific Background : CAMK2gamma is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that

have been implicated in diverse effects of hormones and neurotransmitters. CAMK2gamma has six alternatively spliced variants that encode

six different isoforms. Some of these variants have been identified in human tumors (1). Transgenic mice expressing a partially

calcium-independent mutant form of CAMK2gamma showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an

increase in the life span of double-positive thymocytes (2). There was an increase in the number of T cells in the secondary lymphoid organs

that had acquired an antigen-dependent memory phenotype.