货品编号: Bioss.bs-1172R 品牌:Bioss 品名:Rabbit Anti-N-cadherin antibody 规格:100ul
产品描述: background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell
adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved
cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At
certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene
product.
Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner
in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal
recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
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