货品编号: 博奥森.bs-11331R 品牌:博奥森 品名:脱中胚蛋白抗体 规格:100ul
产品描述: background: EOMES (eomesodermin homolog), also known as TBR2 (T-box-brain2), is the 686 amino acid human homolog of the
mouse Eomes protein that contains one T-box DNA binding domain. Genes that contain T-box domains encode proteins
that function as transcription factors and are often involved in the regulation of various developmental events. Localized
to the nucleus and expressed in the developing brain, EOMES is thought to be involved in neuronal migration and division
and may play a role in trophoblast development and gastrulation. Silencing of the EOMES gene can cause mutated or
arrested development and may lead to microcephaly disorders which are characterized by reduced head circumference
and a malformed brain.
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