货品编号：博奥森.bs-8596R

品牌：博奥森

品名：G蛋白偶联受体120抗体

规格：50ul

产品描述：

GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377

amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated

long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy

source. They also employ various physiological responses through their GPCRs. One such

response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion

of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules

known as the incretins, which are associated with insulin secreted from the pancreas as a result

of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying.

Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.