货品编号：bioss.bs-0127M

品牌：bioss

品名：Mouse Anti-Bax antibody

规格： 10ul

产品描述：

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or

homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.

This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported

to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which

leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated

by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively

spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].