货品编号: bioss.bs-0782R 品牌:bioss 品名:Rabbit Anti-IL-6 antibody 规格:20ul/支
产品描述: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded
protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases
or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the
serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this
gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus
and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].
Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential
role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces
myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic
progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction
and acts to increase the breakdown of fats and to improve insulin resistance.
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