规格：100ul

研究领域 心血管免疫学细胞膜受体 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat, 产品应用 WB=1:500-2000ELISA=1:500-1000Flow-Cyt=3ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 121kDa 细胞定位 细胞膜分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human CD163:101-200/1156<Extracellular> 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍

CD163 is a 130 kDa membrane glycoprotein. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for

the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that

evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes,

and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and

dexamethasone. Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into

plasma or cell supernatant.