品牌： Bioss

品名： Anti-AIF调亡诱导因子抗体

规格： 100ul

研究领域：肿瘤 细胞生物 染色质和核信号 神经生物学 细胞凋亡 细胞周期蛋白 线粒体

抗体来源：Rabbit

克隆类型：Polyclonal

交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

产品应用：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量：57kDa

细胞定位：细胞核 细胞浆 线粒体

性 状：Liquid

浓 度：1mg/ml

免 疫 原：KLH conjugated synthetic peptide derived from human AIF:131-230/613

亚 型：IgG

纯化方法：affinity purified by Protein A

储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed：PubMed

产品介绍：This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found

in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this

protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product

induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause

combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.

Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome

10. [provided by RefSeq, May 2010].