货品编号： Bioss.bs-4600R 品 牌： Bioss 品 名： Anti-TIMP-1金属蛋白酶组织抑制因子-1抗体 规 格： 100ul 研究领域 肿瘤细胞生物神经生物学细胞凋亡生长因子和激素激酶和磷酸酶合成与降解 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep, 产品应用 ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 21kDa 细胞定位 分泌型蛋白 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human TIMP-1:131-207/207 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the

matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In

addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation

in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible

in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes

suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin

I gene and is transcribed in the opposite direction. [provided by RefSeq].