货品编号Bioss.bs-0982R
品牌Bioss
品名Anti-phospho-NFKB p65 (Ser536)磷酸化细胞核因子抗体
规格100ul
研究领域肿瘤 染色质和核信号 信号转导 转录调节因子 激酶和磷酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 Flow-Cyt=1μg /test (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量61kDa
细胞定位细胞核 细胞浆
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the phosphorylation site of Ser536:FS(p-S)IA
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the
cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves
to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2
bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with
the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this
gene. [provided by RefSeq, Sep 2011].
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