货品编号Bioss.bs-10027R

品牌Bioss

品名Anti-NCR1细胞毒性受体NK-p46抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量31kDa

细胞定位细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human CD335:198-206/304 <Extracellular>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors

that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two

extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane

domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule

involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous

tumor cells and pathogen-infected cell lines.