货品编号Bioss.bs-10423R-100ul

品牌Bioss

品名Anti-Collagen II型胶原蛋白/胶原蛋白1/1型胶原蛋白/I型胶原a1抗体

规格100ul

研究领域肿瘤 细胞生物 免疫学

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量130kDa

细胞定位细胞外基质 分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Collagen I:1051-1150/1464

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet

repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin

and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome,

and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene

for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called

dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.