货品编号Bioss.bs-1432R

品牌Bioss

品名Anti-CD68CD68抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Cow,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量37kDa

细胞定位细胞浆 细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human CD68:1-130/354 <Extracellular>

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and

tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP)

family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the

cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds

to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family.

Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment

and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.