货品编号Bioss.bs-1453R

品牌Bioss

品名Anti-Caveolin-1细胞质膜微囊蛋白-1抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1µg/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量20kDa

细胞定位细胞浆 细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Caveolin-1:2-120/178

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found

in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling

integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene

candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next

to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex.

By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a

single transcript from this gene. [provided by RefSeq].