货品编号： Bioss.bsm-33193M 品 牌： Bioss 品 名：Anti-Cytochrome C细胞色素C单克隆抗体 规 格： 100ul 研究领域 肿瘤心血管细胞生物神经生物学细胞凋亡线粒体 抗体来源 Mouse 克隆类型 Monoclonal 克隆号 6B10 交叉反应 Human,Mouse,Rat, 产品应用 WB=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 14kDa 细胞定位 细胞浆线粒体 性状 Liquid 浓度 1mg/ml 免疫原 Recombinant human Cytochrome C Protein: 亚型 IgG 纯化方法 affinity purified by Protein G 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed PubMed

产品介绍 Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where

it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest

has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure

to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for

the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family

molecule that is a key effector of apoptosis.